A faster way to discovery
At Alithea Genomics we are committed to developing solutions that simplify and streamline the generation of "big RNA data", which we believe will constitute the foundation of tomorrow's research and medicine.
Our technologies enable our clients to discover new biomarkers and develop new drugs at a fraction of the costs and time as compared to what was possible before.
Our products
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24-, 96- and 384-sample multiplexing formats.
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Suitable for projects of all sizes.
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Multiple UDIs included for smaller pool sizes.
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BRB-seq + seamless globin depletion.
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Available for human and mouse blood RNA.
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Validated on fresh blood and PAXgene® blood RNA samples.
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Bypasses RNA extraction.
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Lysis buffer compatible with 2D cultures and organoids.
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Ideal for large-scale screening projects.
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High sensitivity BRB-seq with modified TSO.
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Input RNA amount as low as 5pg.
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Validated on single cells, single organoids and FFPE samples.
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Learn more: get an overview of our products and services
The product catalog at a glance:
All our products are linked by a common theme: to enable simple, fast and cost-efficiency generation of "big RNA data".
Our unique technology, called Bulk RNA Barcoding and sequencing (BRB-seq), constitutes the foundation of a growing product portfolio.
The catalog contains an overview of all available products, services, technical information, main features, ordering info and success stories.
Our Technology
The core principle of our technology is the use of highly optimized sets of barcoded primers, the BRB-seq oligos. They are used to "tag" individual RNA samples in a unique and sample-specific manner.
Our oligos are optimized and validated to enable the generation of consistent, reproducible and uniform RNA sequencing data.
RNA barcoding occurs at the first step of the library preparation workflow, after which, samples can be pooled and processed together in one single tube.
In essence, BRB-seq provides a drastic decrease
in reagents use, plastic consumption
and manual operations.
With BRB-seq, the more samples, the better!
Custom globin blockers
We have developed custom globin blockers that seamlessly integrate with the existing BRB-seq workflow.
The resulting Blood BRB-seq is the state-of-the-art solution for blood transcriptomics studies of all sizes based on gene expression analysis.
Optimised, gentle but efficient lysis buffer
By combining an efficient but gentle lysis buffer, which is compatible with downstream enzymatic processing, the Cell Lysate BRB-seq system enables to begin library preparation directly on cell lysates, without having to go through the trouble of cumbersome RNA extraction.
Chemically modified
template-switching oligo
We re-imagined the original BRB-seq workflow by introducing a chemically modified templated-switching oligo, which enables us to push the boundaries of low-input RNA sequencing. Our High-Sensitivity BRB-seq workflow can take input samples with as low as 5pg of RNA.
Coming soon
Coming soon
Coming soon
Areas of Interest
BLOOD TRANSCRIPTOMICS
DRUG DISCOVERY
INFECTIOUS DISEASES
AND IMMUNOLOGY
MODEL SYSTEMS
“We are committed to helping our academic and industrial clients maximize their efficiency and gain productivity while reducing the overall costs of their gene expression experiments and analyses.”
Riccardo Dainese, CEO Alithea Genomics
Questions or interest? Let's talk.
Set up here a video meeting appointment with one of our RNA experts to explore how our solutions can help you make more discoveries, faster.
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