Riccardo DaineseApr 252 minModel SystemsA story of fruit flies, sleep and RNA-seqLife scientists have been using the Drosophila Melanogaster, commonly known as the fruit fly, for over a century now as a model system to...
Riccardo DaineseApr 252 minImmunology and infectious diseasesWhole blood RNA-seq to guide COVID-19 treatmentCurrently, there is no efficient way to predict how the immune system will respond to COVID-19 exposure. The immune response could range...
Riccardo DaineseApr 252 minDrug DiscoveryFunctional drug screening: microarray vs RNA-seqThere are several sensitive methods for investigating gene expression on a large scale. Microarrays are widely used for rapid,...
Riccardo DaineseApr 252 minBlood TranscriptomicsBlood transcriptomics: sequence deeper or sequence more samples? Expression Quantitative Trait Loci (eQTLs) in large-scale RNA-seq studies are of great medical interest as they can be employed to...
Riccardo DaineseApr 252 minImmunology and infectious diseasesSingle and bulk RNA-seq working together to boost immuno-oncologyTumours are very heterogeneous. Somewhat counterintuitively, this heterogeneity goes beyond the malignant cells. In fact, tumours are...